Building of Capitella Teleta Model

Capitella teleta lives in the humus-rich bottom of the ocean and feeds on swallowing sediment and digesting the organic debris and tiny organisms therein. Studies on the embryonic development of Capitella teleta found that neural precursor cells migrate during the brain development of Capitella teleta, which is significantly different from the neurogenesis process of Drosophila and vertebrates. Capitella teleta is an important species for studying the evolution of bilaterian body patterns. Moreover, with the acquisition of the high-quality genome of Capitella teleta, the light-sensitive gene opsin was knocked out using CRISPR/Cas9 technology, and the phenotype was successfully obtained. It is marked that the genome editing technology of Capitella teleta is established. Compared with other marine polychaetes, Capitella teleta has the advantage of a better platform for functional verification and is an excellent animal model that can help us deeply understand the mechanism of organism establishment and regeneration.

Fig 1. Capitella teleta is an annelid (Seaver E C, 2016)

Our Services

Our feedback tells us that customers value our high level of customer service, including fast turnaround times, excellent quality control, and attention to detail. We pride ourselves on delivering a high level of customer service no matter who we work with and no matter what service we provide. Our services are listed as follows, but are not limited to:

• Genetic functional studies
• Gene annotation
• Gene editing
• Disease modeling
  we use genome engineering to build Capitella teleta models which are essential tools in life science research，in order to faithfully establish human disease models.
• Embryological and molecular genetic studies of Capitella teleta
  Capitella teleta is an invaluable tool for the study of evolutionary development. We can establish tissue- and temporal-specific reporter lines to study organismal development, morphology, and function. Transcriptional reporters allow monitoring of the evolution of biological processes.

Why use Capitella teleta model?

• Capitella teleta is a segmented annelid worm whose phylogenetic position, stable genome, environmental resilience, early development, and ability to regenerate allow it to provide insights into its evolutionary success.
• Capitella teleta has a unique combination of capabilities and resources that make it a suitable system for addressing many biological questions in the fields of evolution and development.
• Because Capitella teleta is an experimental system, hypotheses arising from bioinformatics analyzes can be directly tested by functional genomic studies.

CD BioSciences is a professional service provider for the marine biology industry. Our Capitella teleta model building services can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Reference

• Seaver E C. Annelid models I: Capitella teleta[J]. Current Opinion in Genetics & Development, 2016, 39: 35-41.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).