Building of Threespine Stickleback Model

The repeated adaptations of Threespine Stickleback to freshwater make them prime organisms for the study of parallel evolution. For decades, the stickleback has been considered one of the most important model systems for studying adaptation. The stickleback can be used to study the adaptation process of vertebrates in the natural environment. In particular, it reveals the importance of ongoing genetic variation for rapid adaptation in vertebrate species compared with the prevalence of de novo mutations. This species has several attributes that make it an excellent model organism: small size, high abundance, wide geographical distribution, high fecundity, and moderate generation time. The stickleback has been used as a model system to identify the genomic basis of highly complex traits, such as behavior and host-microbiome and host-parasite interactions. Sticklebacks have a variety of different ecotypes, showing a variety of phenotypic characteristics. Ecotypes are easily identified in the laboratory, families are large and rapidly evolving, and quantitative trait locus analysis is possible, making the three-spine stickleback a versatile model organism that can address a wide variety of such biological problems.

Our Services

CD BioSciences is a contract research organization (CRO) specializing in Threespine Stickleback research. We provide tailor-made solutions to help biological, genetic, pharmaceutical companies and academic research institutions accelerate the research and development process and increase the value of Threespine Stickleback.

• Development of a bioenergetics model for the Threespine Stickleback
  We parameterized the bioenergetics model of the Threespine Stickleback to determine the mass and temperature dependence functions of maximal expenditure and conventional respiration cost. The bioenergetics model performed well when used to predict independent, paired measures of consumption and growth observed from a single wild stickleback population.
• Development of an evolutionary genomics model for the Threespine Stickleback
  Using a wide range of genomic resources, including linkage maps, high-quality reference genomes, and developmental genetics tools, our scientists constructed the Threespine Stickleback model, gained insight into the genomic basis of adaptation, and studied genomic changes that control vertebrate traits.
• Development of a behavioural neuroscience model for the Threespine Stickleback

Why use Threespine Stickleback?

Threespine Stickleback has proven valuable in the fields of ecology and genetic evolution. For companies seeking genetic mechanism research, Threespine Stickleback's modeling provides predictive answers in a fraction of the time.

• Cost & time efficiency
  The stickleback has been used as a model system to identify the genomic basis of highly complex traits, such as behavior and host-microbiome and host-parasite interactions.
• Behavior similar & conservation
  Many axes of natural behavioral change studied in sticklebacks are similar to human behavioral changes, such as risk-taking behavior, sensation-seeking, extraversion, and aggression. Sticklebacks have many of the advantages of traditional model organisms, and we can study them in the wild.

CD BioSciences is a professional service provider for the marine biology industry. Our Threespine Stickleback model building services can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).