Development of Marine Analgesic Drug

Nonsteroidal anti-inflammatory drugs (NSAIDs) and narcotic analgesics (opioids) are widely used to reduce pain, reduce fever, and inflammation. However, opioids and NSAIDs only relieve 50% of pain in about 30% of patients. NSAIDs are known to increase the risk of gastrointestinal ulcers and bleeding, heart disease, and kidney disease. Potentially serious side effects of opioids include decreased ability to breathe and low blood pressure. Therefore, research to find alternative ways to treat pain is critical. Natural products provide a promising source of new chemical entities that can be used in the treatment of pain. Seventy percent of the world's surface is covered by water bodies, and marine natural resources within it would be a potential source of metabolites with analgesic/antinociceptive activity. Ziconotide, for example, was the first marine drug approved for the treatment of pain. Also known as Prialt, it was originally extracted from the marine snail Conus magus.

Our Services

We provide marine analgesic drug development services and work closely with medicinal chemistry, ADME, structural biology and fragment-based drug discovery teams to deliver results within challenging timelines.

• Sample Collection of Marine Organism
  We provide preparation of alcohol extract and preparation of water extract.
• Extraction and Purification of Marine Analgesic Compounds
  Our dedicated purification team provides chiral and achiral purification services using preparative supercritical fluid chromatography (Prep-SFC) and preparative high-performance liquid chromatography (prep-HPLC). Our experts produce high-quality compounds from milligrams to hundreds of kilograms in a fast turnaround time.
• Screening & Profiling Assays
  Our assay development and screening biologists combine candidate compound and biological expertise with state-of-the-art instrumentation to deliver a service tailored to your needs.
• Acute Toxicity Studies
• Evaluation of Analgesic Activity
  We evaluate the analgesic activity of candidate compounds using the formalin test procedure.

Our Advantages

• Deep marine expertise: With our strong background in marine biology, we possess an in-depth understanding of marine ecosystems and the potential they hold for antiparasitic drug discovery.
• Cutting-edge technologies: We leverage state-of-the-art technologies and methodologies to accelerate the drug discovery process, providing faster and more efficient outcomes.
• Collaborative approach: We believe in fostering collaborative relationships with our clients, working closely with them at every step to ensure their goals are met.
• Accuracy and quality: We uphold stringent quality standards throughout our research and development processes, ensuring accurate and reliable results that meet regulatory requirements.

CD BioSciences is a professional service provider for the marine biology industry. Our marine analgesic drug development services can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).