Endocrine Disruption Testing

Endocrine-disrupting compounds, which interfere with the action of naturally occurring hormones in humans and animals, have become the focus of scientific attention and alarm among the general public. Authorities around the world have begun to actively regulate these substances and implement screening programs to minimize their environmental impact, requiring manufacturers in all industries to begin testing their products for potential endocrine-disrupting effects.

CD BioSciences has been at the forefront of developing specific tests to identify endocrine disruptors and determine their effects, and we are proud to be the contract research organization of choice for such testing. CD BioSciences is recognized as a commercial leader in endocrine disruptor research using aquatic vertebrate and yeast activity assays. We developed and implemented a set of tools for assessing the potential reproductive effects of sewage and cleaning chemicals on aquatic vertebrates. We emphasize endocrine pathways controlled by estrogens and androgens.

Our Services

Endocrine disruption testing (EDT) is an important test to ensure chemical safety and protect the environment, aquatic organisms, and human health. CD BioSciences specializes in comprehensive services for EDT, including in vitro and in vivo testing, endpoint measurements and endocrine mechanisms of action. Our services are listed as follows, but are not limited to:

Fish endocrine disruption test
Rapid screening for endocrine disruptors
Fish pathology and histology
Laboratory workflow for the entire compound study
Life cycle research
Field assessment of endocrine disruptors

Test Organisms

CD BioSciences began working with EDT many years ago. It enables us to build expertise, insight, technology and historical data sets that you can benefit from. Our historical dataset is especially important for endocrine disruption testing and reflects our innovations in EDT. We have completed endocrine disruptor projects for the following species:

Cyprinella leedsi	Ceriodaphnia dubia	Ceriodaphnia dubia
Chironomus tentans	Leptocheirus plumulosus	Hyalella azteca
Pimephales promelas	Ampelisca abdita	Selenastrum capricornutum
Mysidopsis bahia	Pimephales promelas	Mysidopsis bahia
Daphnia pulex	Menidia beryllina	Menidia beryllina
Arbacia punctulata	Daphnia magna

Our Advantages

Technical expertise in EDT using aquatic vertebrates, particularly fish and amphibians
Experienced team of professionals with specialized skills in endocrinology, ecotoxicology, and chemical analysis
State-of-the-art laboratory equipment, including LC-MS/MS, GC-MS, and transcriptomics equipment, among others
Customized testing services tailored to meet clients' specific needs
Compliant with industry standards and regulatory guidelines

CD BioSciences is a professional service provider for the marine biology industry. Our EDT services can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).