Fermentation of Marine Microalgae to Produce EPA/DHA

In recent years, the study of fatty acid composition of marine microalgae has attracted the interest of scientists from all over the world, not only because marine microalgae are an important source of many long-chain polyunsaturated fatty acids (PUFAs), and studies have found that such fatty acids are harmful to marine animals and humans. It has nutritional and medicinal value, and there is a strong correlation between fatty acid composition and algal taxonomy. Therefore, fatty acid composition can be used as one of the markers for the chemical classification of marine microalgae. Marine microalgae have the peculiar ability to synthesize n-3-PUFAs such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Most of the EPA and DHA in other marine organisms, including fish, are accumulated from microalgae through the food chain, so marine microalgae are another important source of EPA and DHA. The content of EPA and DHA is a very important indicator to measure its nutritional value. Therefore, the research and development of highly unsaturated fatty acids in marine microalgae have received great attention.

Our Services

Our scientists are dedicated to the development of marine unsaturated fatty acids, and our laboratory members have extensive experience in the analytical testing of fatty acid properties. We leverage the experience of our leaders, managers and scientists to effectively meet client requirements for accurate, timely, high-quality results.

• Selection of marine microalgae strain
• Culture of marine microalgae strain
• Separation and purification of EPA and DHA in fermentation broth
• Cryogenic freezing crystallization
• Urea adduction fractionation
• Adsorption separation
• Molecular distillation
• Lipase extraction
• Supercritical fluid extraction

Why we use microalgae to develop EPA and DHA?

• Microalgae grow faster and produce high EPA and DHA.
• The cell structure of microalgae is simple, and its growth and metabolism are easily affected by external conditions. Therefore, the synthesis of EPA and DHA can be promoted by changing the culture conditions, such as temperature, light intensity, medium composition, etc., and the algal strains producing high EPA and DHA can also be screened by genetic engineering methods.
• Large-scale artificial cultivation of microalgae is easy using large outdoor pools, photobioreactors, etc. The culture conditions can be controlled artificially, and stable metabolites can be easily obtained.
• EPA and DHA extracted from microalgae are cholesterol free, free from pesticides and heavy metal pollution

CD BioSciences is a professional service provider for the marine biology industry. Our marine EPA/DHA biosynthesis services can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).