Isolation and Cultivation of Marine Microorganisms

Microbiologists, ecologists, agronomists, taxonomists, and evolutionary biologists are increasingly interested in marine microbial natural products (MMNPs). The discovery of MMNPs is mainly attributed to marine microorganisms. 16 of the 20 marine cancer drugs in clinical trials are produced by bacteria. Therefore, isolating and culturing a new marine microorganism may be a rapid method to search for new MMNPs. Most microbes from the environment (>99.9%) do not colonize the nutrient-rich agar media used in the past to isolate marine bacteria. This limited cultural capacity can be attributed to artificial conditions in most media, such as a lack of essential nutrients for growth. Although a variety of molecular methods are available for the analysis of microbial communities, culture-based analysis is far from redundant, as only the isolation of individual bacterial species in pure culture can fully characterize physiological properties and comprehensively assess application potential (e.g., bioactive compounds). Therefore, the development of isolation and culture methods is the premise for studying marine microorganisms.

Our Services

We provide innovative solutions for microbiology in all areas of marine microbiology. Successfully addressing microbiological challenges and implementing them sustainably in practice are our primary goals. Our services are listed as follows, but are not limited to:

Isolation of Marine Microorganisms
- Single microbial cell isolation
- Streaking for isolation on an agar plate
- The pour plate method
- Isolation of diverse marine microorganism using pretreatment strategies

Pretreatment Strategies	Specific Groups of Marine Microorganisms
Exposure to phenol, dry heat, sucrose-gradient centrifugation, and filtration through cellulose membrane filters	Slow-growing marine bacteria
Sucrose centrifugation method	Nocardia and Actinomycete
Super high-frequency radiation, UV irradiation, extremely high-frequency radiation, and cold shock	Micromonospora, Knoellia, Glycomyces, Actinomadura, Nocardia, Nonomuraea, Nocardiopsis, Rhodococcus, Pseudonocardia, and Streptosporangium genera

Cultivation of Marine Microorganisms
- Rapid microbial detection
- Microencapsulation
- Selection and design of culture media for the biodiversity of marine microbes
- Marine media, including marine agar, nutrient seawater agar, nutrient agar, and thiosulfate-citrate-bile salts-sucrose agar

Why Use Our Marine Microbial Isolation and Cultivation Services?

Turnaround time and price range
Our customer-focused microbial isolation and culture services include a range of sample turnaround times and prices to help our customers prioritize the isolation of their most important microorganisms and optimize the use of their budgets.
Accurate and reliable identification
CD BioSciences uses genotyping methods to identify isolates. In other words, identification is based on DNA sequencing. We use this method because we believe it is the most accurate identification method.

Why Use Our Marine Microbial Isolation and Cultivation Services?

Our Advantages

Fewer defects and bugs
Less time waiting for results
Prevent overproduction
Simplify sample shipping
Streamline inventory
Eliminate unnecessary employee interaction with samples
Reduce processing requirements

CD BioSciences is a professional service provider for the marine biology industry. Our identification and detection services of marine microorganisms can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).