Marine Microbial Production of Lipopolysaccharide Biosurfactant

Marine biosurfactants are amphiphilic surface-active molecules produced by marine microorganisms such as bacteria, fungi and yeast. Marine biosurfactants have attracted attention in pest control due to their low toxicity, high biodegradability, optimal activity under extreme environmental conditions, and environmental friendliness. Meanwhile, the most relevant biosurfactants produced by marine microorganisms exhibit antibacterial, antiadhesion or antibiofilm activity against different pathogenic microorganisms, and some biosurfactants are effective against a broad spectrum of human pathogens, including Gram-positive bacteria and Gram-negative bacteria, and the yeast Candida albicans. High molecular weight biosurfactants are produced by many different marine bacteria, including lipoproteins, proteins, polysaccharides, lipopolysaccharides, or complexes containing several of these structural types. Lipopolysaccharides (LPS) are macromolecules composed of a lipid and a polysaccharide, which are bacterial toxins. They consist of O antigens, an outer nucleus, and an inner core, all linked by covalent bonds, and present in the outer membrane of Gram-negative bacteria. CD BioSciences is a leading provider of surfactant process design and development services to the consumer goods industry and surfactant manufacturers. CD BioSciences utilizes state-of-the-art instrumentation to provide customers with microbial synthesis of LPS biosurfactants.

Fig. 1 Structure of bio/surfactants. (Gürkök S, et al., 2021)

Our Services

CD BioSciences is a leading company providing optimal biosynthesis services. Our talented scientists with extensive experience in biology, chemistry and engineering can avoid common pitfalls in experimental design. Our experts will work closely with you to assist you in designing and optimizing your synthetic route for LPS biosurfactants. Our services are listed as follows, but are not limited to:

• Optimization of production
• Downstream processes optimization
• Isolation of LPS biosurfactants
• Identification of LPS biosurfactants
• Purification and quantification of LPS biosurfactants

The Main Microorganisms Used in Our LPS Biosurfactants Production

The main microorganisms used in our LPS biosurfactants production are Corynebacterium lepus, Penicillium, Spiculisporum, Acinetobacter sp., Rhodococcus, and Erythropolis.

LPS Biosurfactants Synthesis Capabilities

• Varieties of LPS Biosurfactant
  CD BioSciences offers more than 1, 000 biologically active LPS biosurfactant with different research grades. We can also customize LPS that are not in our catalog according to your specific demand.
• Efficient Service
  Our custom LPS biosurfactant services include "fast production" services for urgent orders, aiming to provide you with high-quality LPS biosurfactant efficiently.
• High Quality
  Our standard analyses typically include mass spectrometric analysis and determination of purity (by HPLC).
• Global Shipping
  No matter where you are in the world, we will provide you with global delivery services

Fig. 2 Factors affecting the production of biosurfactants.

CD BioSciences  is a professional service provider for the marine biology industry. Our quantitative analysis services of marine biosurfactant can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Reference

• Gürkök S, Özdal M. Microbial Biosurfactants: Properties, Types, and Production[J]. Anatolian Journal of Biology, 2021(2): 7-12.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).