Process Design and Optimization for Marine Biosurfactant Production

The marine biosphere provides abundant flora and fauna and represents a vast natural resource of important functional commercial-grade products. At CD BioSciences, we produce biosurfactants primarily through marine microorganisms. Compared with chemical surfactants, biosurfactants have lower toxicity and stable properties. The marine microorganisms we use in our production mainly include: Acinetobacter, Arthrobacter, Pseudomonas, Halomonas, Myxomyces, Corynebacterium, Bacillus, Alteromonas sp. In the design and execution of our production process, algal lipid biosurfactants have been found to be commercially attractive due to a range of interesting properties. For example, immunomodulatory activity and low toxicity make it suitable for use in the biomedical industry, as well as high emulsifying properties in the oil and petroleum industry, and bioremediation applications. However, the production of algal lipid biosurfactants in dynamic systems, low potency, and expensive recovery methods result in difficult bioprocessing and high production costs. We separated surface-active compounds from solution by using foam fractionation, a potentially inexpensive and green isolation method that enables the marine bacterium Rhodococcus to produce algal lipid biosurfactants.

Fig. 1 Low-temperature biosurfactants from polar microbes. (Trudgeon B, et al., 2020)

Our Services

CD BioSciences staff have many years of experience in marine biosurfactant process design and optimization, and these studies support the development of a wider range of surfactants. Our labs focus on the efficient delivery of science, compliance, customer service and data. All teams work hard to provide exceptional service, delivering data that fits your schedule.

• Marine biosurfactant synthetic route development
• Marine biosurfactant synthetic route optimization
• Evaluation of screening methods for the isolation of biosurfactant producing marine bacteria
• Breeding of marine bacterial strains

Our Foam Fractionation Technique

Foam fractionation is a separation process in which proteins and other amphiphilic substances are adsorbed to the surface of bubbles. We have increased the separation efficiency of algal lipid surfactants by using foam fractionation techniques. Having a valid simulation model at every time of process development also enables comprehensive process optimization from the beginning of process development.

Our Capabilities

Our liquid separation laboratories are equipped with ultra-high performance liquid chromatography (UPLC), high performance liquid chromatography (HPLC), and liquid chromatography-mass spectrometry (LC-MS) instruments for the separation, identification, and quantification of surfactant.

Our Advantages

• Solving problems with professional knowledge and creativity
• Complex biological data interpretation
• Responsive project management
• Rich experience in marine biosurfactant synthesis process design and optimization
• Broad application area of marine biosurfactant expertise
• Experience in patent strategy

CD BioSciences  is a professional service provider for the marine biology industry. Our synthetic route optimization of marine biosurfactant can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Reference

• Trudgeon B, Dieser M, Balasubramanian N, et al. Low-temperature biosurfactants from polar microbes[J]. Microorganisms, 2020, 8(8): 1183.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).