Aging Model

Overview

Aging is an unavoidable physiological process and is a high-risk influence factor for some major diseases, such as tumors, diabetes, cardiovascular diseases, and neurodegenerative diseases. Therefore, the study of the mechanisms of aging and the delay of aging is of great importance to many researchers, and the establishment of a diversity of aging models is imminent. CD BioSciences provides innovative tools and platforms for studying aging mechanisms, developing anti-aging drugs, and advancing regenerative medicine through the development and application of unique marine organism models. Our marine organism models capitalize on the special characteristics of these organisms, providing researchers with unprecedented opportunities to unravel the mysteries of aging.

Marine organism models for aging research. Figure 1. Identification of a zebrafish mutant, fruehrentner (frnt), exhibiting late phenotypes that resemble normal aging. (Li C, et al., 2020)

Advantages of Our Marine Organism Models

Anti-aging properties. Due to their unique living environment and physiological characteristics, marine organisms exhibit different aging mechanisms and adaptive strategies from terrestrial organisms. Some marine mollusks have extremely long lifespans and remarkable anti-aging properties.
Strong regenerative capacity. Marine organisms, such as sea urchins and starfish, have strong regenerative capacity, which provides valuable research materials for understanding cell regeneration and repair mechanisms.
Low-temperature adaptability. Many marine organisms live in low-temperature environments, and their physiological mechanisms for adapting to low temperatures provide new perspectives for studying antioxidant defense systems.

Applications of Our Marine Organism Models for Aging Research

Aging Mechanism Research

Our team uses different marine organism models further to study the molecular and genetic basis of cellular aging. We provide cell culture, gene editing, and molecular biology technical support to help reveal key mechanisms in the aging process. Through the comprehensive analysis of genomic and environmental factors, we can explore the interaction between genes and the environment in the aging process and understand its impact on lifespan and health.

Anti-aging Drug R&D

We are committed to accelerating the discovery and development of anti-aging drugs by providing high-throughput screening platforms to identify and verify potential anti-aging drug targets and compounds quickly. In the preclinical stage, our marine organism models can be used to evaluate the safety and efficacy of candidate drugs. Detailed efficacy analysis and toxicity assessment can help customers accelerate drug development.

Regenerative Medicine

We provide unique marine organism models and professional services for regenerative medicine research. We support the development of regenerative models, tissue regeneration experiments, and data analysis to further study tissue regeneration and cell repair mechanisms. In addition, our scientists use the regenerative ability of marine organisms to explore methods and strategies for cell therapy through cell isolation, culture, and functional analysis, thereby accelerating the development of cell therapy technology.

Environmental Adaptation and Evolution Research

Our marine organism models provide valuable tools for studying environmental adaptation and evolution. We provide environmental simulation, adaptation experiments, and gene expression analysis to help reveal the impact of environmental changes on aging and health. By comparing the aging mechanisms of different marine organisms, we reveal the evolutionary laws of the aging process. We provide evolutionary analysis, population comparison, and phylogenetic research services to provide new perspectives for understanding human aging.

What Can Our Platform Offer?

Model development. We provide a one-stop service from marine model development, and gene editing to maintenance to ensure high-quality biological models.
Senescence marker detection. We support comprehensive senescence marker detection services, including telomere length, apoptosis, oxidative stress levels, etc., which help to study the aging process in depth.
Genomic and proteomic analysis. We utilize advanced genomic and proteomic analysis techniques to reveal key gene and protein changes in the aging process of marine organisms.
Drug screening and evaluation. Our team puts marine organism models into high-throughput screening and effect evaluation of anti-aging drugs to accelerate the drug development process.

Related Services

With a comprehensive technology platform and a professional team, CD BioSciences is committed to providing clients with one-stop marine organism model development services to accelerate research on aging mechanisms and the discovery of anti-aging drugs. For more information about our services, please contact us.

Reference

Li C, Barton C, Henke K, et al. (2020). celsr1a is essential for tissue homeostasis and the onset of aging phenotypes in the zebrafish[J]. Elife. 9: e50523.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).