Neuroscience Research

Overview

Neurological diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) have become the focus of biomedicine due to the lack of effective cures. Therefore, the establishment of relevant animal models is of great significance for clarifying their causes, pathogenesis, and drug screening. Understanding how nerve cells connect, form networks, and are affected by genetic factors can help us study normal nerve development. CD BioSciences is committed to providing marine organism model development services for neuroscience research, further helping to reveal the structure and function of the nervous system. These models not only provide important tools for basic research but also play a key role in drug development and disease research.

Zebrafish model used in neuroscience research. Figure 1. An overview of the workflow using zebrafish model for NB study. (Li S, et al., 2021)

Main Application Areas

Neural Signaling Research

Our marine organism models have unique advantages in studying neural signaling, such as using the squid model to deeply explore the transmission mechanism between neural signals. Because squid neurons have huge size, our team can accurately perform electrophysiological recordings to observe the function of ion channels and the propagation of action potentials. Through these studies, we can further reveal how the nervous system coordinates information transmission at the molecular and cellular levels, thereby providing a scientific basis for developing new neurological drugs.

Neurodevelopmental Research

Our zebrafish model has played an important role in neurodevelopmental research. Zebrafish embryos are transparent and develop rapidly, allowing us to observe the development of the nervous system in real-time. Through gene editing technologies such as CRISPR/Cas9, we can create zebrafish models with specific gene mutations to study the functions of these genes in neural development. Our research helps to understand how neurons differentiate, migrate, and establish connections during development, which is of great significance for understanding developmental disorders of the human nervous system.

Neurosurgery Research

We provide powerful marine organism models in the field of neurological disease research. Zebrafish and squid models have been widely used to study a variety of neurological diseases such as neurodegenerative diseases, autism, and epilepsy. By creating disease models carrying specific gene mutations, we can simulate the pathogenesis of human neurological diseases and study their pathological mechanisms. Our goal is to discover potential therapeutic targets and intervention strategies through these studies, thereby accelerating drug development for neurological diseases.

Gene Function Research

Because the zebrafish genome is easy to manipulate, we can study the function of specific genes in the nervous system through gene knockout and knock-in experiments. These data not only help to reveal the basic biological functions of genes but also provide new perspectives for understanding genetic neurological diseases. Our research team has rich experience and advanced technology to provide comprehensive support for your gene function research.

Neural Network and Behavior Research

We provide zebrafish models for the study of neural networks and behavior. Zebrafish have a rich variety of behavioral phenotypes, such as learning, memory, movement, and social behavior. By studying these behaviors and the neural networks behind them, we can better understand how the nervous system controls behavior and reveal the neurobiological basis of abnormal behavior. This is of great significance for the study of behavior-related diseases such as autism and depression.

Drug Screening

Our platform provides efficient drug screening services, using marine organism models for high-throughput screening. Our zebrafish model is particularly suitable for drug screening because its embryonic and larval stages are sensitive to drug responses and easy to observe. We can quickly screen compounds with potential therapeutic effects on the nervous system and conduct further functional validation. Through collaboration with pharmaceutical companies and research institutions, we are committed to promoting the development of new drugs, especially new drugs for neurological diseases.

Why Choose Us?

Strong technical support. Our professional team consists of experienced biologists and neuroscientists who can provide customers with comprehensive guidance.
Customized services. We can design solutions based on the different needs of customers.
Short cycle. Our complete technical platform can ensure the delivery of experimental data and results as soon as possible.

Related Services

With its strong capabilities, CD BioSciences is committed to providing reliable services and technical support to help scientists uncover complex problems in the field of neuroscience and promote the research of neurological diseases. If you are interested in our services, please contact us for information.

Reference

Li S, Yeo K S, Levee T M, et al. (2021). Zebrafish as a neuroblastoma model: Progress made, promise for the future[J]. Cells. 10(3): 580.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).